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Filtered Search Results
Medchemexpress LLC Esamisulpride (S)-amisulpride | 71675-92-8 | 99.0% | 369.48 g/mol | C17H27N3O4S | 10MG
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Esamisulpride (S)-amisulpride is the S-enantiomer of amisulpride supplied for research use as a dopamine D2/D3 receptor antagonist with low-nanomolar affinity. It also shows activity at 5-HT7 and is used in pharmacology and behavioral studies related to schizophrenia and depression.
- High chemical purity (99.04%) suitable for research applications.
- Potent D2 and D3 receptor antagonist with low-nanomolar affinity.
- Reported 5-HT7 receptor activity for broader pharmacological profiling.
- Available in small mass quantities appropriate for preclinical experiments.
- Confirmed molecular formula C17H27N3O4S and molecular weight 369.48 g/mol.
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eMolecules 1018678-50-6 | 2-(Difluoromethyl)benzaldehyde | ChemScene | MFCD16875639 | 156.132 | C8H6F2O | 96.000 | FC(F)c1ccccc1C=O | 100mg | 801476742
2-(Difluoromethyl)benzaldehyde | ChemScene | 1018678-50-6 | MFCD16875639 | 156.132 | C8H6F2O | 96.000 | FC(F)c1ccccc1C=O | 100mg | 801476742
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Medchemexpress LLC Tirofiban | 144494-65-5 | 98.4% | 440.60 | 50 MG
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Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist. It inhibits fibrinogen binding to this receptor, leading to antithrombotic activity. It also induces proliferation and migration of endothelial cells by stimulating VEGF production, and significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
- Selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist
- Inhibits fibrinogen binding to the receptor
- Possesses antithrombotic activity
- Induces proliferation and migration of endothelial cells
- Reduces myocardial no-reflow and ischemia-reperfusion injury
- Alleviates myocardial microvascular structural and endothelial dysfunction
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Medchemexpress LLC PRMT5-IN-1 hydrochloride | 99.5% | 455.29 | 10 MG
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PRMT5 IN-1 hydrochloride (compound 9), a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. It can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions. It is for research use only and not sold to patients.
- Potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor
- IC50 of 11 nM for PRMT5/MEP50
- Inhibits the PRMT5/MEP50 complex very rapidly with a Kinact of 0.068 min-1 and a good binding affinity (KI=55 nM)
- Inhibits the expression of cellular sDMA with an IC50 value of 0.012 μM in Granta-519 cells
- Inhibits cell proliferation in a dose-dependent manner with an IC50 value of 0.06 μM in Granta-519 cells
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eMolecules 621-87-4 | Phenoxyacetone | Medchem Express | MFCD00008767 | 150.177 | C9H10O2 | 98.000 | CC(=O)COc1ccccc1 | 500mg | 832657108
Phenoxyacetone | Medchem Express | 621-87-4 | MFCD00008767 | 150.177 | C9H10O2 | 98.000 | CC(=O)COc1ccccc1 | 500mg | 832657108
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Medchemexpress LLC GSK2945 hydrochloride | 00-00-0 | 99.7% | 457.80 g/mol | C20H19Cl3N2O2S | 5 MG
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GSK2945 hydrochloride is the hydrochloride salt of a small-molecule antagonist of the nuclear receptor Rev-erbα, supplied for preclinical research. It has reported EC50 values of 21.5 μM (mouse) and 20.8 μM (human) and has been used to increase CYP7A1 levels and modulate cholesterol metabolism.
- High chemical purity (99.7%).
- Solid form suitable for storage at 4°C; in solution store under nitrogen at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO (~20.83 mg/mL); in vivo formulations and protocols are available for suspension or clear solution preparations.
- Activity: Rev-erbα antagonist with reported EC50 around 21 μM in cell-based assays.
- Provided for research use with supporting assay and formulation data.
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Medchemexpress LLC Nutlin carboxylic acid | 2249750-27-2 | 98.6% | 100 MG
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Nutlin carboxylic acid is a Nutlin 3-based MDM2 ligand designed to form PROTACs (Proteolysis-Targeting Chimeras). These PROTACs operate by harnessing the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. It has a molecular weight of 639.53 and a chemical formula of C32H32Cl2N4O6, appearing as a white to yellow solid.
- Nutlin 3-based MDM2 ligand
- Forms PROTACs via a linker
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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eMolecules 52603-58-4 | N-(2-Aminobenzothiazol-6-yl)benzamide | Oakwood Chemical | MFCD00608286 | 269.320 | C14H11N3OS | 90.000 | Nc1nc2ccc(NC(=O)c3ccccc3)cc2s1 | 100mg | 537683356
N-(2-Aminobenzothiazol-6-yl)benzamide | Oakwood Chemical | 52603-58-4 | MFCD00608286 | 269.320 | C14H11N3OS | 90.000 | Nc1nc2ccc(NC(=O)c3ccccc3)cc2s1 | 100mg | 537683356
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![eMolecules 55120-75-7 | Calcium trifluoromethanesulfonate | ChemScene189.140 | CCaF3O3S | 98.000 | [Ca++].[O-]S(=O)(=O)C(F)(F)F | 25g | 582635116](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502484614.JPG-250.jpg)
eMolecules 55120-75-7 | Calcium trifluoromethanesulfonate | ChemScene189.140 | CCaF3O3S | 98.000 | [Ca++].[O-]S(=O)(=O)C(F)(F)F | 25g | 582635116
Calcium trifluoromethanesulfonate | ChemScene | 55120-75-7189.140 | CCaF3O3S | 98.000 | [Ca++].[O-]S(=O)(=O)C(F)(F)F | 25g | 582635116
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Selleck Chemical LLC Icotinib (BPI-2009H) S2922-200mg
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Icotinib (BPI-2009H) is a potent and specific EGFR inhibitor with IC50 of 5 nM including the EGFR EGFR(L858R) EGFR(L861Q) EGFR(T790M) and EGFR(T790M L858R)
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Medchemexpress LLC HY-110266 5mg Medchemexpress, GN44028 CAS:1421448-26-1 Purity:>98%
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Medchemexpress, HY-110266 5mg GN44028 CAS:1421448-26-1 GN44028 is a hypoxia inducible factor (HIF)-1 inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 444308-32-1 | 1-(4-Fluorophenyl)propan-2-ol | MFCD11934388 | 250mg
Ambeed | (R)-2-Hydroxy-122-triphenylethyl acetate | 1g | 552745424 | A587401 | 95061-47-5 | MFCD00066242 | 332.399 | C22H20O3
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Medchemexpress LLC HY-119243 5mg Medchemexpress, LY2794193 CAS:2173037-97-1 Purity:>98%
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Medchemexpress, HY-119243 5mg LY2794193 CAS:2173037-97-1 LY2794193 is a highly potent and selective mGlu3 receptor agonist ( hmGlu3 K i =0.927 nM， EC 50 =0.47 nM; hmGlu2 K i =412 nM， EC 50 =47.5 nM) [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 2986-60-9 | 3-(Cyclopropylmethoxy)propan-1-amine | Combi-Blocks | MFCD07329912 | 129.203 | C7H15NO | 98.000 | NCCCOCC1CC1 | 1g | 117568667
3-(Cyclopropylmethoxy)propan-1-amine | Combi-Blocks | 2986-60-9 | MFCD07329912 | 129.203 | C7H15NO | 98.000 | NCCCOCC1CC1 | 1g | 117568667
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eMolecules 76666-32-5 | Medchem Express | 3-Methoxyflavonol | 50mg | 446275785 | HY-N6629 | MFCD00017730 | 268.268 | C16H12O4
Medchem Express | 3-Methoxyflavonol | 50mg | 446275785 | HY-N6629 | 76666-32-5 | MFCD00017730 | 268.268 | C16H12O4
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